Detectable urogenital schistosome DNA and cervical abnormalities 6 months after single-dose praziquantel in women with Schistosoma haematobium infection.

@article{Downs2013DetectableUS,
  title={Detectable urogenital schistosome DNA and cervical abnormalities 6 months after single-dose praziquantel in women with Schistosoma haematobium infection.},
  author={Jennifer A Downs and Rodrick Kabangila and Jaco J. Verweij and Hyasinta M Jaka and Robert N Peck and Samwel E Kalluvya and John M. Changalucha and Warren D. Johnson and Lisette van Lieshout and Daniel W. Fitzgerald},
  journal={Tropical medicine & international health : TM & IH},
  year={2013},
  volume={18 9},
  pages={1090-1096}
}
We explored response to single-dose praziquantel therapy in a cohort of 33 women with Schistosoma haematobium infection in rural Mwanza, Tanzania. Women with S. haematobium infection confirmed both by eggs in urine and by polymerase chain reaction (PCR) received single-dose praziquantel and treatment of concomitant sexually transmitted infections. Macroscopic cervical abnormalities were also quantified. After 6 months, microscopically detectable egg excretion was eliminated, but 8 of 33 women… CONTINUE READING