Details Matter: Noise and Model Structure Set the Relationship between Cell Size and Cell Cycle Timing

  title={Details Matter: Noise and Model Structure Set the Relationship between Cell Size and Cell Cycle Timing},
  author={Felix Barber and Po-yi Ho and Andrew W. Murray and Ariel Amir},
  journal={Frontiers in Cell and Developmental Biology},
Organisms across all domains of life regulate the size of their cells. However, the means by which this is done is poorly understood. We study two abstracted “molecular” models for size regulation: inhibitor dilution and initiator accumulation. We apply the models to two settings: bacteria like Escherichia coli, that grow fully before they set a division plane and divide into two equally sized cells, and cells that form a bud early in the cell division cycle, confine new growth to that bud, and… 

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