Detailing intra-lesional venous lumen shrinking in multiple sclerosis investigated by sFLAIR MRI at 7-T

@article{Mueller2014DetailingIV,
  title={Detailing intra-lesional venous lumen shrinking in multiple sclerosis investigated by sFLAIR MRI at 7-T},
  author={Katharina Felicitas Mueller and Joseph Kuchling and Jan M D{\"o}rr and Lutz Harms and Klemens Ruprecht and Thoralf Niendorf and Jens Wuerfel and Friedemann Paul and T Sinnecker},
  journal={Journal of Neurology},
  year={2014},
  volume={261},
  pages={2032-2036}
}
Intra-lesional venous lumen shrinking detectable by MRI was suggested as an in vivo marker of inflammation in multiple sclerosis (MS). In our study mean diameters of pre-, post- and intra-lesional venous sections were determined in 49 patients with MS or clinically isolated syndrome (CIS) using a pixel-wise analysis on susceptibility-weighted fluid-attenuated inversion recovery (sFLAIR) images and T2*-weighted (T2*w) imaging at 7 Tesla (T). We observed post-to-intra-lesional venous lumen… CONTINUE READING
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