Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart.

@article{Georgiadi2012DetailedTA,
  title={Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart.},
  author={Anastasia Georgiadi and Mark Boekschoten and Michael Müller and Sander Kersten},
  journal={Physiological genomics},
  year={2012},
  volume={44 6},
  pages={
          352-61
        }
}
Fatty acids comprise the primary energy source for the heart and are mainly taken up via hydrolysis of circulating triglyceride-rich lipoproteins. While most of the fatty acids entering the cardiomyocyte are oxidized, a small portion is involved in altering gene transcription to modulate cardiometabolic functions. So far, no in vivo model has been developed enabling study of the transcriptional effects of specific fatty acids in the intact heart. In the present study, mice were given a single… 
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