Detailed scenario of the acid-base behavior of prototropic molecules in the subdomain-IIA pocket of serum albumin: results and prospects in drug delivery.

@article{Datta2014DetailedSO,
  title={Detailed scenario of the acid-base behavior of prototropic molecules in the subdomain-IIA pocket of serum albumin: results and prospects in drug delivery.},
  author={Shubhashis Datta and Sudipta Panja and Mintu Halder},
  journal={The journal of physical chemistry. B},
  year={2014},
  volume={118 42},
  pages={12153-67}
}
The protein pocket performs magically in controlling, inhibiting, or optimizing various biochemical processes. The elegant 3D disposition of different side chains in the cavity is a key point in accommodating specific ligands. Anion receptors in the subdomain-IIA pocket of serum albumin (SA) prefer to home anionic ligands. Acid-base behavior is an important… CONTINUE READING