Detailed passive cable models of whole-cell recorded CA3 pyramidal neurons in rat hippocampal slices.

@article{Major1994DetailedPC,
  title={Detailed passive cable models of whole-cell recorded CA3 pyramidal neurons in rat hippocampal slices.},
  author={Guy Major and A. U. Larkman and Peter Jonas and Bert J. Sakmann and Julian J B Jack},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1994},
  volume={14 8},
  pages={4613-38}
}
Tight-seal whole-cell recordings were made from cleaned somata of CA3 pyramidal cells deep in hippocampal slices from 19-21-d-old rats. The cells were filled with biocytin, and their voltage responses to short current pulses were recorded. After washout of initial sag, responses scaled linearly with injected current and were stable over time. The dendritic and axonal arbors of four cells were reconstructed and measured using light microscopy. Dendritic spines and axonal boutons were counted and… CONTINUE READING
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