Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma.

@article{Bekri1997DetailedMO,
  title={Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma.},
  author={Soumeya Bekri and Jos{\'e} Ad{\'e}la{\"i}de and Sandra Merscher and Josiane Grosgeorge and F-X Caroli-Bosc and D Perucca-Lostanlen and Philip M. Kelley and Marie Jos{\`e}phe P{\'e}busque and Charles Theillet and Daniel Birnbaum and Patrick Gaudray},
  journal={Cytogenetics and cell genetics},
  year={1997},
  volume={79 1-2},
  pages={125-31}
}
Amplification of loci present on band q13 of human chromosome 11 is a feature of a subset of estrogen receptor positive breast carcinomas prone to metastasis. As many as five distinct amplification units have been described on 11q13. They include particularly a genomic area encompassing the GARP gene at 11q13.5-->q14.1. We have reassessed our current knowledge of this region, located telomeric to CCND1 and EMS1, which is amplified in 7-10% of mammary tumors. The loose definition of the driving… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 57 extracted citations

Similar Papers

Loading similar papers…