Detailed examination of cytoskeletal networks within enteropathogenic Escherichia coli pedestals.

@article{Ruetz2012DetailedEO,
  title={Detailed examination of cytoskeletal networks within enteropathogenic Escherichia coli pedestals.},
  author={Tyson Joel Ruetz and A Wayne Vogl and Julian A Guttman},
  journal={Anatomical record},
  year={2012},
  volume={295 2},
  pages={
          201-7
        }
}
Enteropathogenic Escherichia coli (EPEC) manipulate the cytoskeleton of host intestinal epithelial cells, producing membrane protrusions termed pedestals that the bacteria reside on throughout the course of their infections. By definition pedestals are actin-based structures, however recent work has identified the spectrin cytoskeleton as a necessary component of EPEC pedestals. Here, we investigated the detailed arrangement of the spectrin and actin cytoskeletons within these structures… CONTINUE READING