Detailed analysis of mucosal herpes simplex virus-2 replication kinetics with and without antiviral therapy.

@article{Schiffer2011DetailedAO,
  title={Detailed analysis of mucosal herpes simplex virus-2 replication kinetics with and without antiviral therapy.},
  author={Joshua T. Schiffer and Amalia S Magaret and Stacy S Selke and Lawrence Corey and Anna Wald},
  journal={The Journal of antimicrobial chemotherapy},
  year={2011},
  volume={66 11},
  pages={
          2593-600
        }
}
OBJECTIVES The presence of herpes simplex virus-2 (HSV-2) shedding episodes correlates with transmission to sexual partners and neonates, and some episodes correlate with disease manifestations. HSV-2-targeted guanosine analogues are effective when given on a prophylactic basis, but do not completely eliminate recurrences, asymptomatic shedding or transmission. We sought to describe the impact of twice-daily aciclovir and famciclovir on shedding episodes. METHODS We used pooled results from… CONTINUE READING
Highly Cited
This paper has 93 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS
12 Extracted Citations
34 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 12 extracted citations

94 Citations

050100'12'13'14'15'16'17'18
Citations per Year
Semantic Scholar estimates that this publication has 94 citations based on the available data.

See our FAQ for additional information.

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 34 references

Similar Papers

Loading similar papers…