Detailed analysis of inflammatory and neuromodulatory cytokine secretion from human NT2 astrocytes using multiplex bead array.

@article{Burkert2012DetailedAO,
  title={Detailed analysis of inflammatory and neuromodulatory cytokine secretion from human NT2 astrocytes using multiplex bead array.},
  author={Kristina Burkert and Kiebashne Moodley and Catherine Elizabeth Angel and Anna Rayner Brooks and Euan S. Graham},
  journal={Neurochemistry international},
  year={2012},
  volume={60 6},
  pages={573-80}
}
Astrocytes are a very important cell type in the brain fulfilling roles in both neuroimmunology and neurotransmission. We have conducted the most comprehensive analysis of secreted cytokines conducted to date (astrocytes of any source) to determine whether astrocytes derived from the human Ntera2 (NT2) cell-line are a good model of human primary astrocytes. We have compared the secretion of cytokines from NT2 astrocytes with those produced in astrocyte enriched human brain cultures and… CONTINUE READING

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