Detailed account on activation mechanisms of ruthenium coordination complexes and their role as antineoplastic agents.

@article{Pal2018DetailedAO,
  title={Detailed account on activation mechanisms of ruthenium coordination complexes and their role as antineoplastic agents.},
  author={Mousumi Pal and Utpal Nandi and Debaraj Mukherjee},
  journal={European journal of medicinal chemistry},
  year={2018},
  volume={150},
  pages={419-445}
}
Ruthenium (Ru) complexes are known for their promising anticancer activity presumably due to octahedral coordination geometry, slow ligand exchange rate, the range of different oxidation states and target specificity. This review article summarizes the physicochemical processes which are responsible for the selectivity of Ru complexes toward cancer cells… CONTINUE READING