Destruction of the locus coeruleus or the dorsal NE bundle does not alter the release of punished responding by ethanol and chlordiazepoxide.

@article{Koob1984DestructionOT,
  title={Destruction of the locus coeruleus or the dorsal NE bundle does not alter the release of punished responding by ethanol and chlordiazepoxide.},
  author={G. F. Koob and K Thatcher-Britton and Donald R. Britton and Darryn C Roberts and Floyd E. Bloom},
  journal={Physiology & behavior},
  year={1984},
  volume={33 3},
  pages={479-85}
}
The hypothetical involvement of central noradrenergic projections in the manifestation of "anxiety" and the "anti-anxiety" effects of alcohol and benzodiazepines was tested in an operant conflict situation by examining the effects of destruction of this noradrenergic system on response rates. Rats were trained on a Geller-Seifter conflict test [9] modified for incremental shock [21], in which two food-reinforced lever press components were separated by a time-out. Responses during the "food… CONTINUE READING