Destruction of preantral follicles in adult rats by 4-vinyl-1-cyclohexene diepoxide.

@article{Flaws1994DestructionOP,
  title={Destruction of preantral follicles in adult rats by 4-vinyl-1-cyclohexene diepoxide.},
  author={Jodi Anne Flaws and J K Doerr and I. Glenn Sipes and Patricia B. Hoyer},
  journal={Reproductive toxicology},
  year={1994},
  volume={8 6},
  pages={509-14}
}
4-vinyl-1-cyclohexene diepoxide (VCD) is known to destroy oocytes in ovaries of immature rats. Since ovaries functionally differ between immature and adult animals, we examined the effect of VCD on oocytes in adult rats. Adult (58 days) and immature (28 days) rats were injected daily (30 days) with vehicle or VCD. Each group contained 10 rats. During this… CONTINUE READING