Despair of repair.

  title={Despair of repair.},
  author={Martin Stangel and H.-P. Hartung},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={72 1},
Intravenous immunoglobulins in multiple sclerosis Originally, intravenous immunoglobulins (IVIg) were designed to provide replacement therapy for patients with hypogammaglobulinaemia. Fortuitously, Imbach et al discovered in the early 1980s that these preparations were beneficial in idiopathic thrombocytopenic purpura.1 Since then, IVIg has been tried, at least experimentally, in almost every disease of a presumed autoimmune nature,2,3 and several uncontrolled studies evaluating potential… CONTINUE READING