Facing Counterfeit Medications in Sexual Medicine. A Systematic Scoping Review on Social Strategies and Technological Solutions.
- Sexual medicine
The counterfeit phenomenon is a steadily growing issue, with PDE5i being the most counterfeited medication with potentially large harmful effects on unaware consumers. Expand
Fiber-Array-Based Raman Hyperspectral Imaging for Simultaneous, Chemically-Selective Monitoring of Particle Size and Shape of Active Ingredients in Analgesic Tablets
- Medicine, Materials Science
A new fiber-array-based Raman hyperspectral imaging technique is presented for direct simultaneous in-situ monitoring of three different active pharmaceutical ingredients- acetylsalicylic acid, acetaminophen and caffeine- in analgesic tablets, which enables a chemically selective, noninvasive assessment of the distribution of the active ingredients down to 1 µm spatial resolution. Expand
Minimalist strategies applied to analysis of forensic samples using elemental and molecular analytical techniques - A review.
- Medicine, Chemistry
- Analytica chimica acta
Analytical techniques for elemental analysis, such as Raman spectroscopy, and ambient ionization mass spectrometry are discussed, and some representative examples are presented that involve in situ analysis, counterfeit bank notes and documents, post-mortem and bone analyses, and forensic analysis of drugs, glass, fingerprints, biological fluids and explosives. Expand
A methodological inter-comparison study on the detection of surface contaminant sodium dodecyl sulfate applying ambient- and vacuum-based techniques
- Materials Science, Medicine
- Analytical and Bioanalytical Chemistry
This systematic inter-comparative approach produced and characterized sodium dodecyl sulfate films mimicking contamination on inorganic and organic substrates, with potential use as reference materials for ambient techniques, i.e., ambient mass spectrometry (AMS), infrared and Raman spectroscopy, to reliably determine amounts of contamination. Expand
A framework for the statistical analysis of mass spectrometry imaging experiments
- Computer Science
This research proposes a novel spatial shrunken centroids framework for performing classification and segmentation of MS imaging experiments with feature selection and provides Cardinal, a free and open-source R package for processing, visualization, and statistical analysis of MS Imaging experiments. Expand
Probabilistic Segmentation of Mass Spectrometry (MS) Images Helps Select Important Ions and Characterize Confidence in the Resulting Segments*
- Computer Science, Medicine
- Molecular & Cellular Proteomics
Spatial shrunken centroids is introduced, a statistical model-based framework for both supervised classification and unsupervised segmentation that expresses both spatial and multivariate nature of the data using probabilistic modeling. Expand
Quantification of selected antidepressants and antipsychotics in clinical samples using chromatographic methods combined with mass spectrometry: A review (2006-2015).
- Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
High specificity in combination with high sensitivity makes chromatography coupled with single or tandem mass spectrometry of selected antidepressants and antipsychotics of selected drugs an attractive complementary method to traditional procedures used in routine practice for TDM. Expand
The interaction of keV cluster and MeV ions with insulating materials.
- Materials Science
Secondary ion mass spectrometry (SIMS) is a well-known surface analysis technique with numerous applications in materials science. In recent years various types of primary ion beams have emerged to… Expand
Different speciation for bromine in brown and red algae, revealed by in vivo X‐ray absorption spectroscopic studies
- Biology, Medicine
- Journal of phycology
This study uses a noninvasive, synchrotron‐based technique, X‐ray absorption spectroscopy, for addressing in vivo bromine speciation in the brown algae Ectocarpus siliculosus, Ascophyllum nodosum, and Fucus serratus, and red algae. Expand
Functional effects of cytochrome P450 variants on drug metabolism and adverse drug reactions: developing and extending high throughput P450 protein technology platforms
This paper aims to provide a chronology of the events that led to and culminated in the publication of the United States Declaration of Independence and the Declaration of the Rights of the USA. Expand