Desomorphine Goes “Crocodile”

@article{Gahr2012DesomorphineG,
  title={Desomorphine Goes “Crocodile”},
  author={Maximilian Gahr and Roland Wolfgang Freudenmann and Christoph Hiemke and Ingo M. Gunst and Bernhard J. Connemann and Carlos Sch{\"o}nfeldt-Lecuona},
  journal={Journal of Addictive Diseases},
  year={2012},
  volume={31},
  pages={407 - 412}
}
A systematic review was conducted to identify the available data for the term Krokodil, which is a jargon expression for an allegedly new drug. Krokodil seems to be a mixture of several substances and was first used in Russia in 2003, with a tremendous increase in the number of addicted individuals since then. The psychoactive core agent of Krokodil is desomorphine, an opioid-analogon that can be manufactured by boiling tablets containing codeine and other ingredients. The procedure results in… 
“ Krokodil ” : The drug that kills 1
Psychotropic substances use and abuse have become a real global problem. Up to now, heroin is still one of the most abused drugs, however its consumption is in sharp decline in favor of Krokodil,
Orally ingestion of krokodil in Spain: report of a case.
TLDR
The case of a user of krokodil and the clinical symptoms of oral ingestion are presented and the simplicity of the process of obtaining the substance from desomorphine, together with its high availability and low cost, contribute toward consumers' self-sufficiency.
“Krokodil”—A Menace Slowly Spreading Across the Atlantic
Krokodil (also known as crocodile, croc, krok, and poor man's heroin) is a suspension of desomorphine as the core substance with contaminants like iodide, phosphorous, and heavy metals, which are the
Krokodil—Morphine’s Deadly Derivative
TLDR
The use of Krokodil is seen most commonly in the Ukraine and Russia, particularly in Siberia, however use has been recorded in Moscow and 27 other Russian cities, Kiev and 24 other Ukrainian cities, Kazakhstan, and other Kazakh regions bordering Russia.
New case of krokodil (desomorphine) use
TLDR
A 27-year-old female with past medical history of intravenous opioid dependence for 5–6 years and gastroesophageal reflux disease who presented with ulcerations of the posterior aspects of her arms bilaterally is treated with intravenous antibiotics and intensive wound care and was observed for opiate withdrawal.
DARK Classics in Chemical Neuroscience: Krokodil.
  • E. Alves
  • Biology
    ACS chemical neuroscience
  • 2020
TLDR
The synthesis of krokodil produces several other morphinans, in addition to desomorphine, which warrants further study as possible analgesic alternatives to morphine.
Lethal endomyocarditis caused by chronic “Krokodil” intoxication
TLDR
This is the first report of an Italian case of lethal krokodil abuse, that occurred in a 39-year-old man, who died suddenly after transportation to the Emergency Department for hyperthermia associated with sweating, dyspnoea and tachycardia.
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