Desmoplastic small round cell tumor with atypical immunohistochemical profile and rhabdoid-like differentiation.

@article{Liang2014DesmoplasticSR,
  title={Desmoplastic small round cell tumor with atypical immunohistochemical profile and rhabdoid-like differentiation.},
  author={Li Liang and Nina Tatevian and Meenakshi B. Bhattacharjee and Kuojen Tsao and John Hicks},
  journal={World journal of clinical cases},
  year={2014},
  volume={2 8},
  pages={367-72}
}
Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive malignant neoplasm of unknown origin, and is comprised of small round cells with a characteristic desmoplastic stroma. DSRCT typically expresses epithelial, mesenchymal and neural markers simultaneously. We describe a case of DSRCT with an atypical immunohistochemical profile and rhabdoid-like tumor cells on electron microscopy. In the present case, the neoplastic cells were positive only for vimentin, desmin (cytoplasmic… CONTINUE READING