• DOI:10.1016/j.fitote.2014.07.022
Corpus ID: 35634109

Desmodeleganine, a new alkaloid from the leaves of Desmodium elegans as a potential monoamine oxidase inhibitor.

@article{Zhi2014DesmodeleganineAN,
  title={Desmodeleganine, a new alkaloid from the leaves of Desmodium elegans as a potential monoamine oxidase inhibitor.},
  author={K. Zhi and Z. Yang and Danfeng Shi and X. Yao and Ming-gang Wang},
  journal={Fitoterapia},
  year={2014},
  volume={98},
  pages={
          160-5
        }
}

• K. Zhi, Z. Yang, +2 authors Ming-gang Wang
• Published 2014
• Biology, Medicine
• Fitoterapia

Desmodeleganine (1), a new potential monoamine oxidase inhibitor, along with three known alkaloids, bufotenin (2), hydroxy-N, N-dimethyltryptamine N(12)-oxide (3), 2-(5-methoxy-1H-indol-3-yl)-N, and N-dimethylethylamine (4) were isolated from the leaves of Desmodium elegans. Their structures were elucidated by IR, MS, 1D and 2D NMR spectra. 1 showed strong monoamine oxidase inhibitory activity with IC50 value of 13.92 ± 1.5 μM, when the IC50 value of iproniazid as a standard was 6.5 ± 0.5 μM… Expand

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