Desipramine treatment of alcoholism.

  title={Desipramine treatment of alcoholism.},
  author={Beniko Mason and James H. Kocsis},
  journal={Psychopharmacology bulletin},
  volume={27 2},
Depression has been related to relapsed drinking in alcoholics striving to maintain sobriety. Treatment with tricyclic antidepressants might reverse or prevent depressive symptoms related to relapse, and may reverse biochemical abnormalities hypothesized to underlie both depression and alcoholism, thus helping to prolong abstinence in recovering alcoholics. This is a preliminary report of the findings of an ongoing 6-month, double-blind, placebo-controlled trial of desipramine (DMI) in recently… CONTINUE READING