Designing the nanobiointerface of fluorescent nanodiamonds: highly selective targeting of glioma cancer cells.

@article{Slegerova2015DesigningTN,
  title={Designing the nanobiointerface of fluorescent nanodiamonds: highly selective targeting of glioma cancer cells.},
  author={Jitka Slegerova and Miroslav H{\'a}jek and Ivan Řehoř and Franti{\vs}ek Sedl{\'a}k and Jan {\vS}tursa and Martin Hrub{\'y} and Petr Cigler},
  journal={Nanoscale},
  year={2015},
  volume={7 2},
  pages={
          415-20
        }
}
Core-shell nanoparticles based on fluorescent nanodiamonds coated with a biocompatible N-(2-hydroxypropyl)methacrylamide copolymer shell were developed for background-free near-infrared imaging of cancer cells. The particles showed excellent colloidal stability in buffers and culture media. After conjugation with a cyclic RGD peptide they selectively targeted integrin αvβ3 receptors on glioblastoma cells with high internalization efficacy. 

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