Designing multiple ligands - medicinal chemistry strategies and challenges.

@article{Morphy2009DesigningML,
  title={Designing multiple ligands - medicinal chemistry strategies and challenges.},
  author={Richard J Morphy and Zoran Rankovic},
  journal={Current pharmaceutical design},
  year={2009},
  volume={15 6},
  pages={
          587-600
        }
}
It has been widely recognised over the recent years that parallel modulation of multiple biological targets can be beneficial for treatment of diseases with complex etiologies such as cancer asthma, and psychiatric disease. In this article, current strategies for the generation of ligands with a specific multi-target profile (designed multiple ligands or… CONTINUE READING