Designing degradable hydrogels for orthogonal control of cell microenvironments

  title={Designing degradable hydrogels for orthogonal control of cell microenvironments},
  author={Prathamesh M Kharkar and Kristi L Kiick and April M Kloxin},
  booktitle={Chemical Society reviews},
Degradable and cell-compatible hydrogels can be designed to mimic the physical and biochemical characteristics of native extracellular matrices and provide tunability of degradation rates and related properties under physiological conditions. Hence, such hydrogels are finding widespread application in many bioengineering fields, including controlled bioactive molecule delivery, cell encapsulation for controlled three-dimensional culture, and tissue engineering. Cellular processes, such as… CONTINUE READING


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