Designing Opioids That Deter Abuse

  title={Designing Opioids That Deter Abuse},
  author={Robert B Raffa and J V Pergolizzi and Edmundo Mu{\~n}iz and Robert Taylor and Jason S Pergolizzi},
  booktitle={Pain research and treatment},
Prescription opioid formulations designed to resist or deter abuse are an important step in reducing opioid abuse. In creating these new formulations, the paradigm of drug development target should be introduced. Biological targets relating to the nature of addiction may pose insurmountable hurdles based on our current knowledge and technology, but products that use behavioral targets seem logical and feasible. The population of opioid abusers is large and diverse so behavioral targets are more… CONTINUE READING
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