Design principles of sensory processing in cerebellum-like structures

  title={Design principles of sensory processing in cerebellum-like structures},
  author={Patrick D. Roberts and Christine V. Portfors},
  journal={Biological Cybernetics},
Cerebellum-like structures are compared for two sensory systems: electrosensory and auditory. The electrosensory lateral line lobe of mormyrid electric fish is reviewed and the neural representation of electrosensory objects in this structure is modeled and discussed. The dorsal cochlear nucleus in the auditory brainstem of mammals is reviewed and new data are presented that characterize the responses of neurons in this structure in the mouse. Similarities between the electrosensory and… 

Single-neuron recordings from unanesthetized mouse dorsal cochlear nucleus.

The findings are generally consistent with the model of DCN function that has been developed in the cat and the gerbil, suggesting that this in vivo mouse preparation will be a useful tool for future studies of auditory physiology.

Listening to another sense: somatosensory integration in the auditory system

This review explores the process of multisensory integration from anatomical, physiological, functional, functional and pathological aspects and focuses on the convergence between auditory and somatosensory inputs in each ascending auditory station.

The Contribution of Brainstem and Cerebellar Pathways to Auditory Recognition

It is reasoned that plasticity in the cerebellar pathways underpins implicit learning of spectrotemporal information necessary for sound and speech recognition, and could support a range of auditory processing functions such as streaming, habituation, and the integration of auditory feature information such as pitch.

Are mushroom bodies cerebellum-like structures?

  • S. Farris
  • Biology
    Arthropod structure & development
  • 2011

The Cerebellum

In addition to its direct role in motor control, the cerebellum is necessary for several types of motor learning, most notably learning to adjust to changes in sensorimotor relationships.

Auditory-Somatosensory Integration in Dorsal Cochlear Nucleus Mediates Normal and Phantom Sound Perception.

It is demonstrated here that somatosensory stimulation alters sound-evoked firing rates and temporal representations of sound for tens of milliseconds through synaptic modulation of intrinsic excitability, suggesting tinnitus development is linked to STDP, presenting a potential target for pharmacological or neuromodulatory tinn Titus therapies.


Heterogeneous spiking behavior in vertical cells and distinct pharmacology between the timing and intensity pathways are studied.

Responses to Social Vocalizations in the Dorsal Cochlear Nucleus of Mice

It is found that fusiform cells in the DCN respond in a heterogeneous manner to vocalizations, and that these neurons can use distortion products as a mechanism for encoding ultrasonic vocalizations.



What's a cerebellar circuit doing in the auditory system?

Integrative Functions in the Mammalian Auditory Pathway

A Ascending and Descending Auditory Pathways Form the Cochlea and their Possible Role in Pattern Recognition of Natural Sounds and Feature Detection by the Auditory Cortex are studied.

Bidirectional synaptic plasticity in the cerebellum-like mammalian dorsal cochlear nucleus

  • K. FujinoD. Oertel
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2002
The dorsal cochlear nucleus integrates acoustic with multimodal sensory inputs from widespread areas of the brain and its sensitivity to antagonists of N-methyl-d-aspartate and metabotropic glutamate receptors differs in fusiform and cartwheel cells.

Sensory processing and corollary discharge effects in the mormyromast regions of the mormyrid electrosensory lobe. I. Field potentials, cellular activity in associated structures.

The neuronal responses to sensory stimuli and to corollary discharge signals associated with the motor command that drives the electric organ discharge (EOD) are described.

The generation and subtraction of sensory expectations within cerebellum-like structures.

The generation of sensory expectations within cerebellum-like structures of four distinct groups of fishes, including Mormyridae; Rajidae; Scorpaenidae; and Apteronotidae, is described and it is indicated that the negative image is probably generated by means of anti-Hebbian synaptic plasticity at the parallel fiber to principal cell synapse.

Circuitry and Function of the Dorsal Cochlear Nucleus

This chapter discusses the response properties of DCN neurons in the context of its neural organization and related to data on the functional role of the DCN in hearing, paying most attention to data from the cat.

Pre-receptor profile of sensory images and primary afferent neuronal representation in the mormyrid electrosensory system

It is concluded that each receptor encodes information coming from the whole scene in a manner that may seem ambiguous when seen from a single point and that, in order to extract specific object features, the brain must process the electric image represented over the whole sensory surface.

Temporal and frequency characteristics of cartwheel cells in the dorsal cochlear nucleus of the awake mouse.

It is shown that cartwheel cells respond well to tonal stimuli in the awake mouse and they have a well-defined characteristic frequency that corresponds to the tonotopic organization of the DCN, which suggests that at this primary auditory structure, processing of sound at one frequency can be modified by sounds of different frequency.

Facilitation of acoustic responses of cartwheel neurons of the cat dorsal cochlear nucleus

The findings indicate that inhibitory interneurons such as cartwheel cells can participate in complex adaptive acoustic signal processing.