Design of simulated moving bed and Varicol processes for preparative separations with a low number of columns.

@article{Pais2003DesignOS,
  title={Design of simulated moving bed and Varicol processes for preparative separations with a low number of columns.},
  author={L. Pais and A. Rodrigues},
  journal={Journal of chromatography. A},
  year={2003},
  volume={1006 1-2},
  pages={
          33-44
        }
}
  • L. Pais, A. Rodrigues
  • Published 2003
  • Chemistry, Environmental Science, Medicine
  • Journal of chromatography. A
  • Simulated moving bed (SMB) chromatography has received significant attention in the last decade, particularly as regards the production of very valuable products, such as enantiomerically pure pharmaceutical compounds. Recent applications in the pharmaceutical industry use SMB systems containing a low total number chromatographic columns, usually four to eight. This paper deals with the modeling and simulation of SMB systems with only four, five and six columns. In particular, two modeling… CONTINUE READING
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