Design of oral insulin delivery systems.

@article{Wong2010DesignOO,
  title={Design of oral insulin delivery systems.},
  author={Tin Wui Wong},
  journal={Journal of drug targeting},
  year={2010},
  volume={18 2},
  pages={79-92}
}
The possibility of administering insulin orally in replacement of painful subcutaneous route has been investigated over years but with varying degree of success. Nanoparticles, microparticles, hydrogel, capsule, tablet, and film patch are designed to deliver insulin orally. They are largely formulated with polymeric adhesive, protease inhibitor, insulin aggregation inhibitor, and functional excipients to induce transcellular, paracellular, Peyer's patches, or receptor-mediated transport of… CONTINUE READING

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