Design of interior-functionalized fully acetylated dendrimers for anticancer drug delivery.


In this study, dendrimers was synthesized by introducing functional groups into the interior pockets of fully acetylated dendrimers. NMR techniques including COSY and 2D-NOESY revealed the molecular structures of the synthesized dendrimers and the encapsulation of guest molecule such as methotrexate within their interior pockets. The synthesized polymeric… (More)
DOI: 10.1016/j.biomaterials.2011.09.016

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