Design of immunogenic peptides from Mycobacterium tuberculosis genes expressed during macrophage infection.

Abstract

In vitro diagnosis of MTB-infection uses MTB-proteins coded for by genes of the region of differentiation 1 (RD1) of the MTB genome. This study wants to test if proteins preferentially expressed during MTB-intracellular growth might provide new targets for the diagnosis of MTB-infection. To this end seventy-five multiepitopic HLA-promiscuous MTB-peptides… (More)
DOI: 10.1016/j.tube.2009.03.005

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