Design of a sustainable prepolarizing magnetic resonance imaging system for infant hydrocephalus

@article{Obungoloch2018DesignOA,
  title={Design of a sustainable prepolarizing magnetic resonance imaging system for infant hydrocephalus},
  author={Johnes Obungoloch and Joshua R. Harper and Steven Consevage and Igor M. Savukov and Thomas Neuberger and Srinivas Tadigadapa and Steven J. Schiff},
  journal={Magnetic Resonance Materials in Physics, Biology and Medicine},
  year={2018},
  volume={31},
  pages={665-676}
}
ObjectivesThe need for affordable and appropriate medical technologies for developing countries continues to rise as challenges such as inadequate energy supply, limited technical expertise, and poor infrastructure persist. Low-field magnetic resonance imaging (LF MRI) is a technology that can be tailored to meet specific imaging needs within such countries. Its low power requirements and the possibility of operating in minimally shielded or unshielded environments make it especially attractive… 

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References

SHOWING 1-10 OF 38 REFERENCES

Non-cryogenic anatomical imaging in ultra-low field regime: hand MRI demonstration.

Design of a mobile, homogeneous, and efficient electromagnet with a large field of view for neonatal low-field MRI

TLDR
The cryogen-free system presented here demonstrates that this electromagnet with a ferromagnetic housing can be optimized for MRI with an enhanced and homogeneous magnetic field.

Low-Cost High-Performance MRI

TLDR
It is contended that these practical ultra-low magnetic field implementations of MRI (<10 mT) will complement traditional MRI, providing clinically relevant images and setting new standards for affordable (<$50,000) and robust portable devices.

Low Field (0.02 T) Nuclear Magnetic Resonance Imaging of the Brain

TLDR
Six cases of cerebral lesions studied with an MR imager operating at a field strength of 0.02 T (200 G) are described, which is the lowest field strength reported in clinical MR imaging.

A readout magnet for prepolarized MRI

TLDR
The authors' initial work on low‐frequency reception indicates that it will be possible to obtain comparable image signal‐to‐noise ratio to an MRI scanner operating at the same polarizing field strength.

Theory of gradient coil design methods for magnetic resonance imaging

The process to produce an MR image includes nuclear alignment, RF excitation, spatial encoding, and image formation. In simple terms, an magnetic resonance imaging (MRI) system consists of five major

Endoscopic Treatment versus Shunting for Infant Hydrocephalus in Uganda

TLDR
This single‐center study involving Ugandan infants with postinfectious hydrocephalus showed no significant difference between endoscopic ETV–CPC and ventriculoperitoneal shunting with regard to cognitive outcomes at 12 months.

Costs and benefits of neurosurgical intervention for infant hydrocephalus in sub-Saharan Africa.

TLDR
The results of this study suggest that neurosurgical intervention has a cost/DALY averted comparable to other surgical interventions that have been evaluated, as well as a favorable benefit-cost ratio.

Two‐dimensional imaging in a lightweight portable MRI scanner without gradient coils

As the premiere modality for brain imaging, MRI could find wider applicability if lightweight, portable systems were available for siting in unconventional locations such as intensive care units,

Rapid polarizing field cycling in magnetic resonance imaging

TLDR
With this modular hardware design, the 0.4-T polarizing coil of a wrist-sized PMRI scanner is successfully ramped at up to 100 T/s without causing image artifacts or otherwise degrading data acquisition.