Design of a multicenter trial to evaluate long-term life-style intervention in adults with high-normal blood pressure levels. Trials of Hypertension Prevention (phase II). Trials of Hypertension Prevention (TOHP) Collaborative Research Group.

@article{Hebert1995DesignOA,
  title={Design of a multicenter trial to evaluate long-term life-style intervention in adults with high-normal blood pressure levels. Trials of Hypertension Prevention (phase II). Trials of Hypertension Prevention (TOHP) Collaborative Research Group.},
  author={Patricia R. Hebert and Roel J. Bolt and Nemat O. Borhani and Nancy R. Cook and Jerome D. Cohen and Jeffrey A. Cutler and Jack F. Hollis and L. H. Kuller and Normal L Lasser and Albert Oberman},
  journal={Annals of epidemiology},
  year={1995},
  volume={5 2},
  pages={130-9}
}
Phase II of the Trials of Hypertension Prevention (TOHP) is a multicenter, randomized trial sponsored by the National Heart, Lung, and Blood Institute designed to test whether weight loss alone, sodium reduction alone, or the combination of weight loss and sodium reduction will decrease diastolic (DBP) and systolic blood pressure (SBP) as well as the incidence of hypertension (DBP > or = 90 mm Hg, SBP > or = 140 mm Hg, and/or use of antihypertensive medications) in subjects with high-normal DBP… CONTINUE READING

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