Design of Polyelectrolyte Multilayers to Promote Immunological Tolerance.

Abstract

Recent studies demonstrate that excess signaling through inflammatory pathways (e.g., toll-like receptors, TLRs) contributes to the pathogenesis of human autoimmune diseases, including lupus, diabetes, and multiple sclerosis (MS). We hypothesized that codelivery of a regulatory ligand of TLR9, GpG oligonucleotide, along with myelin-the "self" molecule… (More)

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Cite this paper

@article{Tostanoski2016DesignOP, title={Design of Polyelectrolyte Multilayers to Promote Immunological Tolerance.}, author={Lisa H. Tostanoski and Yu-Chieh Chiu and James I. Andorko and Ming Guo and Xiangbin Zeng and Peipei Zhang and Walter Royal and Christopher M Jewell}, journal={ACS nano}, year={2016} }