Design of Pluronic-Based Formulation for Enhanced Redaporfin-Photodynamic Therapy against Pigmented Melanoma.

@article{Pucelik2016DesignOP,
  title={Design of Pluronic-Based Formulation for Enhanced Redaporfin-Photodynamic Therapy against Pigmented Melanoma.},
  author={Barbara Pucelik and Luis G Arnaut and Grazyna Stochel and Janusz M Dąbrowski},
  journal={ACS applied materials & interfaces},
  year={2016},
  volume={8 34},
  pages={
          22039-55
        }
}
The therapeutic outcome of photodynamic therapy (PDT) with redaporfin (a fluorinated sulfonamide bacteriochlorin, F2BMet or LUZ11) was improved using Pluronic-based (P123, F127) formulations. Neither redaporfin encapsulated in Pluronic nor micelles alone exhibited cytotoxicity in a broad concentration range. Comprehensive in vitro studies against B16F10… CONTINUE READING