Design of PLGA based nanoparticles for imaging guided applications.

Abstract

An amphiphilic Gd(III) complex has been efficiently loaded in polylactic-co-glycolic acid nanoparticles (PLGA-NPs) to yield a novel, high sensitive magnetic resonance imaging (MRI) contrast agent for imaging guided drug delivery applications. As the Gd(III) complex is soluble in organic solvents, the nanoparticles were prepared as oil/water emulsions. PLGA… (More)
DOI: 10.1021/mp5002747

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@article{Mariano2014DesignOP, title={Design of PLGA based nanoparticles for imaging guided applications.}, author={Rodolfo Nicol{\'a}s Mariano and Diego Alberti and Juan Carlos Cutrin and Simonetta Geninatti Crich and Silvio Aime}, journal={Molecular pharmaceutics}, year={2014}, volume={11 11}, pages={4100-6} }