Design of Clinical Trials Evaluating Dietary Interventions in Patients With Functional Gastrointestinal Disorders

@article{Yao2013DesignOC,
  title={Design of Clinical Trials Evaluating Dietary Interventions in Patients With Functional Gastrointestinal Disorders},
  author={Chu Kion Yao and Peter R. Gibson and Susan J Shepherd},
  journal={The American Journal of Gastroenterology},
  year={2013},
  volume={108},
  pages={748-758}
}
Clear guiding principles for the design and conduct of dietary intervention trials in functional gastrointestinal disorders (FGID) are lacking. This narrative review examines the specific challenges associated with the design and reporting in dietary intervention trials. Dietary intervention trials need to address the collinearity between food, nutrients, and bioactive components that obscure the relationship between food and their effects in the gut. Randomized, double-blinded, placebo… CONTINUE READING
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