Design for DNA separation medium using bacterial cellulose fibrils.

Abstract

In this paper, we present a novel DNA separation medium using bacterial cellulose fibrils. Bacterial cellulose has an intrinsic three-dimensional micrometer- to nanometer-scale network structure. Addition of this material to a low-concentration polymer solution (<5 cP) enables high-resolution electrophoretic separation of DNA, even for fragments of 10-100-bp or single-nucleotide polymorphism. The newly designed medium consists of a double mesh: a 10-nm flexible mesh derived from a conventional polymer medium containing 10-nm to 1-microm rigid pores made up of 10-microm bacterial cellulose fragments.

Cite this paper

@article{Tabuchi2005DesignFD, title={Design for DNA separation medium using bacterial cellulose fibrils.}, author={Marl Tabuchi and Yoshinobu Baba}, journal={Analytical chemistry}, year={2005}, volume={77 21}, pages={7090-3} }