Design and synthesis of pyrankacin: a pyranmycin class of broad-spectrum aminoglycoside antibiotic.

@article{Rai2006DesignAS,
  title={Design and synthesis of pyrankacin: a pyranmycin class of broad-spectrum aminoglycoside antibiotic.},
  author={R. Rai and Hsiao-Nung Chen and P. G. Czyryca and J. Li and C. Chang},
  journal={Organic letters},
  year={2006},
  volume={8 5},
  pages={
          887-9
        }
}
  • R. Rai, Hsiao-Nung Chen, +2 authors C. Chang
  • Published 2006
  • Chemistry, Medicine
  • Organic letters
  • A novel broad-spectrum aminoglycoside antibiotic, pyrankacin, has been prepared. In addition to the synthetic innovation in dideoxygenation and regioselective Staudinger reduction, we have obtained prominent antibacterial activity against several clinically important pathogens in the course of this work. 
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