Design and statistical methods in studies using animal models of development.

@article{Festing2006DesignAS,
  title={Design and statistical methods in studies using animal models of development.},
  author={Michael Fw Festing},
  journal={ILAR journal},
  year={2006},
  volume={47 1},
  pages={5-14}
}
Experiments involving neonates should follow the same basic principles as most other experiments. They should be unbiased, be powerful, have a good range of applicability, not be excessively complex, and be statistically analyzable to show the range of uncertainty in the conclusions. However, investigation of growth and development in neonatal multiparous animals poses special problems associated with the choice of "experimental unit" and differences between litters: the "litter effect." Two… CONTINUE READING
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