Design and statistical methods in studies using animal models of development.

  title={Design and statistical methods in studies using animal models of development.},
  author={Michael Fw Festing},
  journal={ILAR journal},
  volume={47 1},
Experiments involving neonates should follow the same basic principles as most other experiments. They should be unbiased, be powerful, have a good range of applicability, not be excessively complex, and be statistically analyzable to show the range of uncertainty in the conclusions. However, investigation of growth and development in neonatal multiparous animals poses special problems associated with the choice of "experimental unit" and differences between litters: the "litter effect." Two… CONTINUE READING
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A Student’s Guide to the Analysis of Variance

  • MJ Roberts, R. Russo
  • London: Routledge.
  • 1999
Highly Influential
4 Excerpts

Guidelines for the design and statistical analysis of experiments using laboratory animals

  • Festing MFW, Altman DG.
  • ILAR J 43:233-243.
  • 2002

The Design of Animal Experiments

  • MFW Festing, P Overend, R Gaines Das, M Cortina Borja, M. Berdoy
  • London: Laboratory Animals Ltd.
  • 2002
1 Excerpt

Mighty mice

  • Festing MFW, Fisher EMC.
  • Nature 404:815.
  • 2000

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