Design and microwave facilitated green synthesis of 2-[4-(3-carboxymethyl, methoxy carbonylmethyl-2,4-dioxo and 4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-phenoxy]-2 and 3-methyl propionic acid ethyl ester derivatives: a novel structural class of antidyslipidemic agents


An interesting hybrid molecular framework comprising of benzylidenethiazolidin-4-one, chalcone and fibrate was designed and synthesized (BRF1–12) in order to develop safe and efficacious compounds for the treatment of dyslipidemia, and related complications such as atherosclerosis. The synthesized derivatives were characterized by Fourier transform infrared… (More)
DOI: 10.1007/s00044-017-1875-0


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