Design and evaluation of multifunctional nanocarriers for selective delivery of coenzyme Q10 to mitochondria.


Impairments of mitochondrial functions have been associated with failure of cellular functions in different tissues, leading to various pathologies. We report here a mitochondria-targeted nanodelivery system for coenzyme Q10 (CoQ10) that can reach mitochondria and deliver CoQ10 in adequate quantities. Multifunctional nanocarriers based on ABC miktoarm… (More)
DOI: 10.1021/bm201538j