Design and construction of higher-order structure and function in proteinosome-based protocells.

@article{Huang2014DesignAC,
  title={Design and construction of higher-order structure and function in proteinosome-based protocells.},
  author={Xin Huang and Avinash J Patil and Mengting Li and Stephen Mann},
  journal={Journal of the American Chemical Society},
  year={2014},
  volume={136 25},
  pages={
          9225-34
        }
}
The design and construction of higher-order structure and function in proteinosome microcompartments enclosed by a cross-linked membrane of amphiphilic bovine serum albumin/poly(N-isopropylacrylamide) (BSA-NH2/PNIPAAm) nanoconjugates is described. Three structure/function relationships are investigated: (i) differential chemical cross-linking for the control of membrane disassembly and regulated release of encapsulated genetic polymers; (ii) enzyme-mediated hydrogel structuring of the internal… CONTINUE READING
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