Design and characterization of novel read-out systems for a capacitive DNA sensor

@article{Venuto2006DesignAC,
  title={Design and characterization of novel read-out systems for a capacitive DNA sensor},
  author={Daniela De Venuto and Bruno Ricc{\`o}},
  journal={Microelectronics Journal},
  year={2006},
  volume={37},
  pages={1610-1619}
}
This paper presents novel read-out electronic systems for a fast DNA label-less detection. The capacitive shift due to the hybridization effect is monitored by means of a charge sensitive amplifier and a differential stage. The systems provide an A/D conversion and an evaluation of the capacitive shift amount with a resolution of 11 bit. The read-out solutions demonstrate the ability to identify a 0.01% variation on the capacitive value of the sensor. The investigated techniques are suitable… CONTINUE READING
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