Design and characterization of an injectable tendon hydrogel: a novel scaffold for guided tissue regeneration in the musculoskeletal system.

@article{Farnebo2014DesignAC,
  title={Design and characterization of an injectable tendon hydrogel: a novel scaffold for guided tissue regeneration in the musculoskeletal system.},
  author={Simon Farnebo and Colin Yi-Loong Woon and Taliah Schmitt and Lydia-Marie Joubert and Maxwell Y Kim and Hung H Pham and James Chang},
  journal={Tissue engineering. Part A},
  year={2014},
  volume={20 9-10},
  pages={1550-61}
}
A biocompatible hydrogel consisting of extracellular matrix (ECM) from human tendons is described as a potential scaffold for guided tissue regeneration and tissue engineering purposes. Lyophilized decellularized tendons were milled and enzymatically digested to form an ECM solution. The ECM solution properties are assessed by proteome analysis with mass spectrometry, and the material's rheological properties are determined as a function of frequency, temperature, and time. In vivo application… CONTINUE READING

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