Design and characterization of a new drug nanocarrier made from solid-liquid lipid mixtures.

@article{GarcaFuentes2005DesignAC,
  title={Design and characterization of a new drug nanocarrier made from solid-liquid lipid mixtures.},
  author={Marcos Garc{\'i}a-Fuentes and Maria Jose Castro Alonso and D. Torres},
  journal={Journal of colloid and interface science},
  year={2005},
  volume={285 2},
  pages={590-8}
}
The classical lipid nanoparticles that have been proposed for drug delivery are composed of solid lipids. Due to their composition, these nanoparticles have a limited drug loading and controlled release capacity. The present work was aimed at modifying the inner structure of nanoparticles made of tripalmitin, lecithin, and poly(ethylene glycol) (PEG)-stearate with the incorporation of a liquid lipid (Miglyol 812 oil). The composition and structural organization of the components of the… CONTINUE READING
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