Design and assessment of a microfluidic network system for oxygen transport in engineered tissue.

@article{Kang2013DesignAA,
  title={Design and assessment of a microfluidic network system for oxygen transport in engineered tissue.},
  author={Tae-Yun Kang and Jung Min Hong and Jin Woo Jung and James J Yoo and Dong-Woo Cho},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2013},
  volume={29 2},
  pages={
          701-9
        }
}
Oxygen and nutrients cannot be delivered to cells residing in the interior of large-volume scaffolds via diffusion alone. Several efforts have been made to meet the metabolic needs of cells in a scaffold by constructing mass transport channels, particularly in the form of bifurcated networks. In contrast to progress in fabrication technologies, however, an approach to designing an optimal network based on experimental evaluation has not been actively reported. The main objective of this study… CONTINUE READING