Design and application of chitosan microspheres as oral and nasal vaccine carriers: an updated review

@inproceedings{Islam2012DesignAA,
  title={Design and application of chitosan microspheres as oral and nasal vaccine carriers: an updated review},
  author={Mohammad Ariful Islam and Jannatul Firdous and Y J Choi and Cheol-Heui Yun and Chong-su Cho},
  booktitle={International journal of nanomedicine},
  year={2012}
}
Chitosan, a natural biodegradable polymer, is of great interest in biomedical research due to its excellent properties including bioavailability, nontoxicity, high charge density, and mucoadhesivity, which creates immense potential for various pharmaceutical applications. It has gelling properties when it interacts with counterions such as sulfates or polyphosphates and when it crosslinks with glutaraldehyde. This characteristic facilitates its usefulness in the coating or entrapment of… CONTINUE READING
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