Design and analysis of a synthetic aptamer-based oscillator


We consider a realistic experimental implementation of a negative feedback molecular oscillator built with RNA aptamers proposed in our previous work [1]. This oscillator is composed of two synthetic genes interconnected through their RNA outputs. Regulation of transcription is achieved by controlling the activity of the enzymes rather than the activity of… (More)
DOI: 10.1109/ACC.2015.7171135

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