Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis

@inproceedings{Vasdev2016DesignAP,
  title={Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis},
  author={Neil Vasdev and Thomas Lee Collier},
  booktitle={Pharmaceuticals},
  year={2016}
}
Column-switching high performance liquid chromatography (HPLC) is extensively used for the critical analysis of radiolabeled ligands and their metabolites in plasma. However, the lack of streamlined apparatus and consequently varying protocols remain as a challenge among positron emission tomography laboratories. We report here the prototype apparatus and… CONTINUE READING