Design and Evaluation of Zidovudine Loaded Natural Biodegradable Microcapsules Employing Colophony Resin as Microencapsulating Agent

@inproceedings{Panda2013DesignAE,
  title={Design and Evaluation of Zidovudine Loaded Natural Biodegradable Microcapsules Employing Colophony Resin as Microencapsulating Agent},
  author={Satyajit Panda and Snigdha Pattnaik and Laxmidhar Maharana and GIRISH BABU BOTTA and Anjan Kumar Mahapatra},
  year={2013}
}
The aim of the present study is to develop and evaluate natural biodegradable microcapsules of zidovudine (AZT) by using colophony resin as microencapsulating agent, which after oral administration could improve the bioavailability of the drug, in order to provide the sustained release to minimize the dose dependent side effects as well as to improve patient compliance. An industrially feasible emulsification-solvent evaporation method was used for preparation of different batches of… CONTINUE READING