Corpus ID: 73699235

Design and Evaluation of Sustained Release Propranolol Hydrochloride Suppositories

  title={Design and Evaluation of Sustained Release Propranolol Hydrochloride Suppositories},
  author={B. V. Basavaraj and S. Devi and S. Bharath and R. Deveswaran and V. Madhavan},
  • B. V. Basavaraj, S. Devi, +2 authors V. Madhavan
  • Published 2013
  • Materials Science
  • The aim of the present study was to prepare a sustained release suppository of propranolol hydrochloride, an antihypertensive drug for rectal administration. Firstly, the microspheres of Propranolol hydrochloride were formulated using ethyl cellulose by non- aqueous solvent evaporation technique. The microspheres were evaluated for percentage yield, particle size, entrapment efficiency, scanning electron microscopy and in vitro drug release studies. The prepared microspheres exhibited prolonged… CONTINUE READING
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