Design and Evaluation of Matrix Tablets of Diltiazem Hydrochloride

Abstract

Delayed release matrix tablets of diltiazem hydrochloride were developed employing combination of hydroxypropyl methyl cellulose and stearic acid as the matrix materials in different proportions. Tablets containing 90 mg of the drug were formulated and made by entrapping the drug in a waxy carrier and then by the conventional wet granulation method… (More)

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